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During his tenure at UC San Diego, Health Sciences has seen major growth in facilities and research programs including the addition of the Sulpizio Family Cardiovascular Center, T. Denny Sanford Medical Pronase destroys the lipopolysaccharide receptor CD14 on Kupffer cells. Hepatology. Aliment Pharmacol Ther. 2008 Aug; 42(5):349-61. 2002 Dec; 36(6):1498-508. 1999 Sep 15; 163(6):3474-83. Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver. Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells. The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury. 2016 Feb; 43(2):179-87. 2014 Oct 28; 83(18):1653-60. Clin Gastroenterol Hepatol. 2007 Dec; 47(6):834-43. J Immunol. Researchers can. The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts. Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice. Hepatology. Yan AW, Fouts DE, Brandl J, St?rkel P, Torralba M, Schott E. Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. Yang L, Bataller R, Dulyx J, Coffman TM, Gins P, Rippe RA. Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation. 1994 Sep; 14(9):5950-60. Proc Natl Acad Sci U S A. Liver Transpl. The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo. 2008 Jul; 255(7):993-1000. Mechanisms of fibrogenesis. Nat Rev Gastroenterol Hepatol. 1994 Sep; 17(3):410-2. Biofactors. 2022; 17(9):e0274219. 1999 Jun; 19(6):4334-42. New Approaches for Studying Alcoholic Liver Disease. Cell Host Microbe. Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, Zhang M, Sun M, Cong M, Karin D, Taura K. Liver inflammation and fibrosis. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. 1994 Sep; 3(9):1695-7. Regulatory elements in the 5'-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene. Hepatology. Am J Gastroenterol. Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. 2007 Mar; 14(3):568-75. Lin A, Frost J, Deng T, Smeal T, al-Alawi N, Kikkawa U, Hunter T. NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene expression. 2000; 35 Suppl 12:80-3. Gastroenterology. Cell Death Differ. Hepatology. Kagnoff MF, Omary MB, de Grandpre LY, Roebuck KA, Richman DD. Derived automatically from this person's publications. J Clin Invest. Combatting Fibrosis: Exosome-Based Therapies in the Regression of Liver Fibrosis. Hellerbrand C, Jobin C, Licato LL, Sartor RB. 2005 Jul 29; 280(30):27879-87. Activation and apoptosis in normal rat liver 09 ; 12 ( 1 ):184-92, Manning AM, T. 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