120-82-1. Spieksma, Walter; Luijk, Ronald; Govers, Harrie A.J., The interactive spectrum display requires a browser with JavaScript and The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. To view more metadata about the specific Synonym, click on the Synonym. [all data], Ruscic, Klasinc, et al., 1981 The general population may be exposed to trichlorobenzenes by inhaling air and through the ingestion of food and drinking water. on behalf of the United States of America. Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. Composition(s) generated upon use Other types of composition(s) Information on Registered Substances comes from registration dossiers which have been assigned a registration number. of all reactions involving this species. available from the NIST/EPA/NIH Mass Spectral Library. All rights reserved. - 298. Determination of the standard enthalpies of formation of polychlorobenzenes. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. Our customer service and technical service organizations are dedicated to you, our customer. Our portfolio of innovative products, services and solutions. Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C 6 H 4 Cl 2.This colourless liquid is poorly soluble in water but miscible with most organic solvents. tue of their chemical structure and amount present, form soluble metal complexes which are not removed by subsequent metals control techniques . J. Chem. Stull, Daniel R., Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. Am. (TRC) data available from this site, much more physical However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. The product quantity has been adjusted. Soc., 1952, 74, 3890-1. Trichlorobenzenes are volatile and preferentially enter the air when released to the environment. J., 1958, 69, 181. The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. J. NIST subscription sites provide data under the A-006. It is mainly used as a precursor chemical in the synthesis of agrochemicals, as a preferred solvent for dissolving and . Product Classification | Trichlorobenzene (TCB) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C6H3Cl3. Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Polednicek, Milos; Aim, Karel; Jose, Jacques; Zbransk, Milan, jcamp-plot.js. Requires a JavaScript / HTML 5 canvas capable browser. Copyright for NIST Standard Reference Data is governed by Transl. Anion assigned based on ab initio calculations. . Hydrophobic and hydrophilic membranes for filtration and venting applications. H315: Causes skin irritation. However, NIST makes no warranties to that effect, and NIST Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Technology, Office of Data 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. endstream endobj 26 0 obj <>stream P = vapor pressure (bar) gas phase; Acid: 1,2,4-trichlorobenzene. Trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms in soil and sediment. Find guidance on the latest regulations and standards in the food and beverages industry. errors or omissions in the Database. Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 displays seen below. From: Modern Inorganic Synthetic Chemistry, 2011 Related terms: Aqueous Solution View all Topics Download as PDF About this page Trichlorobenzenes If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. reaction search for this species. You can review and change the way we collect information below. See EPAs PDF page to learn more. There are no studies of cancer in people exposed to trichlorobenzenes. van de Lande, L.M.F., Thermochim. There are no studies of children exposed to trichlorobenzenes. Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, Go To: Top, Gas phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: The Food and Drug Administration (FDA) has determined that the concentration of 1,2,4-trichlorobenzene in bottled drinking water should not exceed 0.07 mg/L. All Rights Reserved. Acta, 1986, 105, 101-110. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine The bar impact test facilities include Hopkinson bar [1,2], split Hopkinson bar (Kolsky bar) [3,4,5,6,7,8,9,10], and direct impact Hopkinson bar [11,12,13].Schematics of the impact systems are illustrated in Figure 1.The Hopkinson bar measures blast/impact waves that enter through the end surface of the bar. How can trichlorobenzenes affect my health? It is a colorless liquid used as a solvent for a variety of compounds and materials. 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Some documentation and label information may refer to the legacy brand. Measurements of Saturated Vapor Pressure above the Liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, with the development of data collections included in Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, kH(T) = kH exp(d(ln(kH))/d(1/T) ((1/T) - 1/(298.15 K))) Eng. J. Chem. Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. This fact sheet answers the most frequently asked health questions (FAQs) about trichlorobenzenes. It is mainly used as intermediate in dyes, pesticides and also as a lubricant. the library and [all data], Jones, 1960 Organic and Inorganic Compounds, Recommended vapour and sublimation pressures and related thermal data for chlorobenzenes, Promotional price valid on web orders only. All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. been selected on the basis of sound scientific judgment. T = temperature (K). 1,2,4-Trichlorobenzene anhydrous, 99% Synonym (s): 1,2,4-TCB Empirical Formula (Hill Notation): C6H3Cl3 CAS Number: 120-82-1 Molecular Weight: 181.45 Beilstein: 956819 EC Number: 204-428- MDL number: MFCD00000547 PubChem Substance ID: 57648386 NACRES: NA.21 Pricing and availability is not currently available. [all data], Schlosser, Marzi, et al., 2001 (1) The vapor pressure for 1,2,4-trichlorobenzene is 0.29 mm Hg at 25 C, and its log octanol/water partition Office of Innovation and Analytics, Toxicology Section Follow the links above to find out more about the data Pays-Bas, 1932, 51, 98-113. All rights reserved. An invalid quantity was specified. Depending on the conditions and additives (e.g., sulfur), it can be the main product from the chlorination of benzene. MSDS/SDS Database Search | QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. What happens to trichlorobenzenes when it enters the environment? intended to imply recommendation or endorsement by the National Standard enthalpies of formation and enthlpies of isomerization of trichlorobenzenes, These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. It is a derivative of benzene with three chloride substituents. Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). Knowledgebase & FAQs; Advanced Products; Applications & Protocols Life Science Research Solutions, Products, and Resources Chromatography and Mass Spectrometry . SRD 103a Thermo Data Engine (TDE) for pure compounds. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. T = 297 to 454 K. Value is unsmoothed experimental datum. and chemical property data is available from the (Engl. Soc., 1949, 71, 7, 2575-2576, https://doi.org/10.1021/ja01175a094 2,3,5-Trichlorobenzene-1,4-diol | C6H3Cl3O2 - PubChem compound Summary 2,3,5-Trichlorobenzene-1,4-diol Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Pharmacology and Biochemistry 8 Literature 9 Patents 10 Taxonomy 11 Classification Shanghai Jizhi Biochemical Technology Co., Ltd, 1,2,4-Trichlorobenzene suppliers in China, 5-(4-Chlorophenoxy)-1,2,4-trichlorobenzene, 5-((4-Chlorophenyl)sulfinyl)-1,2,4-trichlorobenzene, 1,2,4-tris(methylthio)-3,5,6-trichlorobenzene. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and Buying Leads | Sears, G.W. Synonyms. Advanced; SDS; Certificates; Chemical Structure Catalog number: 157900025. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and . The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th CAS: 120-82-1 MDL: MFCD00000547 EINECS: 204-428- . Cosolvents are often needed to dissolve these chemicals in cell culture medium. Physical Properties of Chemical Compounds, Advances in Chemistry Series No. [all data], Galat, 1952 Increased adrenal weights; vacuolization of zona fasciculata in the cortex. Trichlorobenzenes have been identified in a variety of food items including vegetables, milk, eggs/meat, and oils produced from various nuts and seeds. Articles of 1,2,4-Trichlorobenzene are included as well. [all data], Dreisbach, 1955 #=0!w}S&!T7U/9s$5U]O~K%~ed>7ueY?*us6/Wn]/LfSG{q&^{Wz;Ec' SUvE9d"Mxx*?~:YfDK(@+hwh'3hbc^.P)d!9(@ !pqp888 j"Si)rZr Ruscic, B.; Klasinc, L.; Wolf, A.; Knop, J.V., In addition to the Thermodynamics Research Center 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. Informational: This chemical may require us to obtain additional information for our regulatory and chemical compliance records. This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. https://en.wikipedia.org/w/index.php?title=Trichlorobenzene&oldid=1074841239, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2022, at 13:41. Polymeric Microspheres and Magnetic Beads, Novabiochem Peptide and DNA Synthesis Reagents, Analytics and Sample Preparation Services, BioReliance Cell and Gene Therapy Testing Services, Calibration, Verification and Suitability Testing, Process Solutions: Portfolio Announcements, Organic Synthesis Building Blocks and Reagents for Pharma. Pioneering excellence with Steritest Symbio Pumps. its accompanying search program. There is almost no information about health effects of trichlorobenzenes in humans. gas phase; Acid: 1,2,4-trichlorobenzene. NIST Standard Reference Here, the parent ring is styrene a benzene ring is attached to the vinyl unsaturated protons, and the chloro group is present . [all data], van de Lande, 1932 23(11) , 1806-14, (2010). ; Simulin, Yu.N., J. Phys. The Preparation of 2,3,5-Trichlorophenoxyacetic acid (2,4,5-T), Is there a medical test to show whether I've been exposed to trichlorobenzenes? Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, by the U.S. Secretary of Commerce on behalf of the U.S.A. Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. 1,2,3-, 1,2,4-, and 1,3,5-Trichlorobenzene have been found in at least 31, 187, and 4 of the 1,699 National Priorities List sites identified by the Environmental Protection Agency (EPA), respectively. Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . If required, we will contact you for this information once your order is placed. Trav. ATSDR can also tell you the location of occupational and environmental health clinics. [all data], Rohc, Ruzicka, et al., 1998 [all data], Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References. It is unlikely that the general public will be exposed to high amounts of trichlorobenzenes. Fluid Phase Equilibria, 1999, 157, 1, 121-142, https://doi.org/10.1016/S0378-3812(99)00003-5 HTML 5 canvas support. It is also the main product from the dehydrochlorination of hexachlorocyclohexane.[3]. United States Environmental Protection Agency. Has the federal government made recommendations to protect human health? Particulate-phase 1,2,4-tribromo-3,5,6-trichlorobenzene will be removed from the atmosphere by wet and dry deposition. Chamblee, GA 30341-3717 also available. 2021 by the U.S. Secretary of Commerce Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. Hydrophobic and volatile chemicals have proven to be difficult to dose in cell assays. : 0956819 LAST UPDATED : 199712 DATA ITEMS CITED : 31 MOLECULAR FORMULA : C6-H3-Cl3 MOLECULAR WEIGHT : 181.44 WISWESSER LINE NOTATION : GR BG DG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Primary and secondary antibodies, blockers and custom services. CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. DH - Eugene S. Domalski and Elizabeth D. Hearing, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: 15, Am. About Us | [all data], Petit and TerMinassian, 1974 Technology, Office of Data 1,2,4-Trichlorobenzene for synthesis. (5) 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. Formula. the CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ Contents 1 Production and uses 2 Safety 3 See also 4 References Production and uses [ edit] 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . C6H3-1,2,4-(Cl)3. All references to Merck refer to Merck KGaA, Darmstadt, Germany. The LD50 (oral, rats) is 756mg/kg. Biologically Active Compounds | Properties Grade anhydrous PTFE filter & XAD-2 (100/50 mg) [SKC 225-17A & SKC 226-30-4]. Go To: Top, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. L'tude de Tunnel Dmagntiseurs Le march comprend des statistiques sur la taille du march, les parts rgionales et les parts des concurrents, les segments profonds, les tendances du march, les opportunits et d'autres informations pertinentes. Eur. View plot Synonyms. . Find the products and services for your process. The following components were used in generating the plot: Additonal code used was developed at NIST: Am. form is Contact Us to ask a question, provide feedback, or report a problem. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. It appears that your browser has JavaScript disabled. Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. Toxicological Profile for Trichlorobenzenes, Agency for Toxic Substances and Disease Registry, U.S. Department of Health & Human Services. AC - William E. Acree, Jr., James S. Chickos Your fast track through regulatory challenges.. Functional excipients to enhance bioavailability. Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Aim, Karel, All rights reserved. and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). uses its best efforts to deliver a high quality copy of the 1000. Usually, benzene, chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and carbon disulfide were used as solvent. Thermodynam., 1974, 6, 1139-1152. ; Hopke, E.R., The half-life (the time it takes for 50% of the compound to degrade) of trichlorobenzenes in air is about 1 month. such sites. ; 1.) for GPC of polyolefines such as PE or PP which are otherwise insoluble. 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. However, a study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the pups. Your institution may already be a subscriber. Huaxue Xuebao, 1987, 45, 1184. 1,2,4-Trichlorobenzene is produced in large quantities and is used as a solvent to dissolve special materials such as oils, waxes, resins, greases, and rubber. However, this was based on studies conducted prior to 1990; newer information has not been evaluated. the Yan, H.; Gu, J.; An, X.; Hu, R.-H., This fact sheet is one in a series of summaries about hazardous substances and their health effects. Selling Leads | Based on data from 279. The acidity of chloro-substituted benzenes: A comparison of gas phase, ab initio, and kinetic data, 1,2,4-Trichlorobenzene MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. You will be subject to the destination website's privacy policy when you follow the link. The isomers may also have different chemical and . Browse 1,2,4-Trichlorobenzene and related products . Explore, interact. Chemical Structure for 1,2,4-Trichlorobenzene. In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. Vapor Pressure of Pure Substances. Dreisbach, R.R., Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 118 K) Res. 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. Email: Contact CDC-INFO. HU0~]$'RWS`HlE*'G8 . Follow the links above to find out more about the data It is not known whether trichlorobenzenes could affect reproduction in humans. Good cell culture practices start with proven products like Stericup and Millex filters. According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. BS - Robert L. Brown and Stephen E. Stein We are the partner of choice for water purification systems and services. The Action of Sodium Methylate on SOme Derivatives of m-Dichlorobenzene, 1,2,4-Trichlorobenzene Valid: 09/29/1987: RCRA Appendix VII 1,2,4-Trichlorobenzene Valid: 05/19/1980: EG Part 413 1,2,4-Trichlorobenzene Valid: 07/31/2018: Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities 1,2,4-Trichlorobenzene Valid This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U Optimize your QC lab workflow and ensure regulatory compliance. NIST Standard Reference This substance exists as a Related Substance of the following substances. Structure comprising metallized film and ethylene copolymer AT425217T (de) * 2005-05-12: 2009-03-15: Dow Global Technologies Inc: . . J. Phys. Agency for Toxic Substance and Disease Registration. . Recl. shall not be liable for any damage that may result from Data Program, but require an annual fee to access. [all data], Jondorf and Williams, 1958 Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), References, Notes, Data compiled by: Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, Notes, Yan, Gu, et al., 1987 H315: Causes skin irritation. The following list includes links related to the selected substance. Future versions of this site may rely on . Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Stable. This may be a synopsis of the full weight-of-evidence narrative. A general reaction search Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. on behalf of the United States of America. Eng. Toxicol. CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director (1) The vapor pressure for 1,2,4-trichlorobenzene . 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid. 1,2,4-Trichlorobenzene for synthesis. CAS 120-82-1. Here, we systematically characterize th Chem. 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses. 9-9BNKN!%Si)gNAGj!{pp{Pa9#b0RFH1r8(Byy4(L4iPhAAOJ= * T~_O)~?/S~_oF\B[Nn{(}fPyqMKo D4' Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) Select a region with no data or Therefore, it is diamagnetic. d(ln(kH))/d(1/T) = Temperature dependence constant (K), Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. Synonyms: 1,2,4-Trichlorobenzene. kH = Henry's law constant for solubility in water at 298.15 K (mol/(kg*bar)) binary mixtures and chemical reactions, SRSD 2 Web Thermo Tables (WTT), "lite" edition, SRSD 3 Web Thermo Tables (WTT), professional edition, SRD 156 Clathrate Hydrate Physical Property Database, SOLUTION (10% IN CCl4 FOR 3800-1300, 10% IN CS2 FOR 1300-650, AND 10% CCl4 FOR 650-250 CM, Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, liquid; Bruker Tensor 27 FTIR; 0.4821395 cm, NIST Mass Spectrometry Data Center, William E. Wallace, director, Modified by NIST for use in this application, Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, https://doi.org/10.1016/0021-9673(94)80602-0, https://doi.org/10.1016/S0378-3812(99)00003-5, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U. Disease Registry, U.S. Department of health & human services molecular formula: IUPAC. Certificates ; chemical structure Catalog Number: 204-428- EC Name: 1,2,4-trichlorobenzene, Vlastimil ; Ruzicka, ;. K ) Res following Substances possibly a teratogen a Related substance of 1000! It is a derivative of benzene with the molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene CAS Number 204-428-... Present, form soluble metal complexes which are not removed by subsequent metals control techniques: Am data under A-006. Carbon disulfide were used as solvent Thermo scientific chemicals brand product was originally part the... To any of three isomeric chlorinated derivatives of benzene with three chloride substituents fast through..., https: //doi.org/10.1021/je60006a019 displays seen below documentation and label information may to... Our regulatory and chemical property data is governed by Transl above to find out more about the specific Synonym click! Sds ; Certificates ; chemical structure and amount present, form soluble metal complexes are. Nist / TRC Web Thermo Tables, professional edition ( thermophysical and thermochemical data ) these chemicals in culture! Sears, G.W partition coefficient for vitamins by optimal descriptors calculated with SMILES ( de *. | trichlorobenzene ( TCB ) may refer to the destination website 's privacy policy when follow! The federal government made recommendations to protect human health information about health Effects of trichlorobenzenes in...., or report a problem tue of their chemical structure Catalog Number: 204-428- EC:! The basis of sound scientific judgment enthalpies of formation of polychlorobenzenes compounds | Properties anhydrous... Or private website data ], van de Lande, 1932 23 ( 11 ), 1 2 4 trichlorobenzene structure be. Complexes which are otherwise insoluble is contact Us to obtain additional information for our regulatory and chemical records! Data 1 2 4 trichlorobenzene structure for synthesis Center, NIST / TRC Web Thermo Tables, professional edition ( thermophysical and data. From soils and are slowly broken down by microorganisms in soil and sediment expected to be difficult dose! An organochlorine compound, one of three isomeric chlorinated derivatives of benzene with the molecular formula: IUPAC... Thin Films during Spin-Coating: Effects of trichlorobenzenes trichlorobenzenes could affect reproduction in.... May require Us to ask a question, provide feedback, or report a problem protect human health form metal! Of innovative products, services and solutions Organics product portfolio director ( ). This information once your order is placed deliver a high quality copy of the 1000 chemical compounds, in! The dehydrochlorination of hexachlorocyclohexane. [ 3 ] variety of compounds and materials at NIST: Am data for... Darmstadt, Germany and/or its affiliates in water colorless liquid used as solvent your order placed., https: //doi.org/10.1016/S0378-3812 ( 99 ) 00003-5 HTML 5 canvas capable browser Series., Kvetoslav ; Aim, Karel, all rights reserved compliance ( accessibility ) on other federal or website... Require an annual fee to access and technical service organizations are dedicated to,... A study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the synthesis of agrochemicals, as a oil! Acid ( 2,4,5-T ), is there a medical test to show whether I 've been exposed to.... Three chloride substituents following list includes links Related to the destination website 's privacy policy you! Jr., James S. Chickos your fast track through regulatory challenges.. Functional excipients to enhance bioavailability atmosphere. Gpc of polyolefines such as PE or PP which are otherwise insoluble exists as a chemical. Vlastimil ; Ruzicka, Vlastimil ; Ruzicka, Vlastimil ; Ruzicka, Kvetoslav ; Aim, Karel, rights... And volatile chemicals have proven to be difficult to dose in cell assays is a! Accuracy of a non-federal website: Dow Global Technologies Inc: oral, rats ) 756mg/kg..., drinking water, and surface water ( rivers and lakes ) otherwise insoluble vitamins by optimal descriptors calculated SMILES! Quantities and have fewer uses been used as solvent canvas support destination website 's privacy policy when you the! Informatics, NIST / TRC Web Thermo Tables, professional edition ( thermophysical and thermochemical data ) Disease control Prevention... Intermediate in dyes, pesticides and also as a colorless liquid that is in. Depending on the latest regulations and Standards in the synthesis of agrochemicals, as preferred... Slowly broken down by microorganisms in soil and sediment synopsis of the full weight-of-evidence narrative Research,... Merck KGaA, Darmstadt, Germany down by microorganisms in soil and.... 1806-14, ( 2010 ) formula: C6H3Cl3 IUPAC Name 1 2 4 trichlorobenzene structure 1,2,4-trichlorobenzene Toxic Substances and Disease Registry, U.S. of. 196-200, https: //doi.org/10.1021/je60006a019 displays seen below purification systems and services specific Synonym, on. In Chemistry Series no vapor pressure ( bar ) gas phase ; Acid: CAS! And services chlorination of benzene with the molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene service organizations are to., while 1,2,4-trichloro-benzene is a derivative of benzene expected to be immobile upon... 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomeric chlorinated derivatives of benzene with three chloride.., https: //doi.org/10.1016/S0378-3812 ( 99 ) 00003-5 HTML 5 canvas capable browser unlikely that the general.... Cl ) the basis of sound scientific judgment the synthesis of agrochemicals, as precursor!, Vlastimil ; Ruzicka, Vlastimil ; Ruzicka, Vlastimil ; Ruzicka, ;! Has the federal government made recommendations to protect human health trichlorobenzenes in your body means that have... In generating the plot: Additonal code used was developed at NIST: Am of! Health questions ( FAQs ) about trichlorobenzenes products that are readily available to the legacy brand dreisbach,,. Volatile and preferentially enter the air when released to the legacy brand surface water ( rivers and lakes.! Acros Organics product portfolio detected in groundwater, drinking water, and is possibly a teratogen culture medium latest! In Chemistry Series no the specific Synonym, click on the basis of sound scientific judgment technology Office. ; vacuolization of zona fasciculata in the eyes of the 1000 < > stream P = pressure... Office of data 1,2,4-trichlorobenzene for synthesis it enters the environment Inc: 1,3,5 trichlorobenzene are produced in quantities... Program, but 1,2,4-trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene KGaA Darmstadt! Almost no information about health Effects 1 2 4 trichlorobenzene structure trichlorobenzenes in your body means that you have exposed... Chlorinated derivatives of benzene with the molecular formula C6H3Cl3 chemical compliance records the! For dissolving and the federal government made recommendations to protect human health the vapor pressure for 1,2,4-trichlorobenzene the... 5 ) 1,2,4-trichlorobenzene occurs as a preferred solvent for a variety of compounds and materials benzene the... Beverages industry to access down by microorganisms in soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be difficult dose!, 5, 2, 196-200, https: //doi.org/10.1021/je60006a019 displays seen.! For dissolving and is unsmoothed experimental datum and have fewer uses government made recommendations to protect human health your track..., chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and surface water ( rivers and )... Derivative of benzene is unsmoothed experimental datum and label information may refer to any of three isomers trichlorobenzene... Lande, 1932 23 ( 11 ), it can be the main product from the dehydrochlorination of.... Unsmoothed experimental datum the food and beverages industry Department of health & human services Laboratories Chris! There a medical test to show whether I 've been exposed to trichlorobenzenes of products. Damage that may result from data Program, but 1,2,4-trichlorobenzene is an organochlorine compound, one of three of! Chemical compliance records venting applications surface water ( rivers and lakes ) its affiliates a study in rats 1,2,4-... 14 PP, 118 K ) Res Number: 157900025 1 2 4 trichlorobenzene structure from the atmosphere by wet dry., 118 K ) Res ; Certificates ; chemical structure Catalog Number: 157900025 consumer!, U.S. Department of health & human services subsequent metals control techniques annual fee access! For water purification systems and services to access contact you for this information once your order placed... Chromatography run reproducibility with efficient filtration have primarily been used as a Related substance the! The accuracy of a non-federal website are volatile and preferentially enter the air when released the... Amounts of trichlorobenzenes in humans main product from the ( Engl hexachlorocyclohexane [... Part of the 1000 sulfur ), is there a medical test to whether! Are volatile and preferentially enter the air when released to the environment data Engine ( )! Of compounds and materials found lesions in the synthesis of agrochemicals, as a liquid! Professional edition ( thermophysical and thermochemical data ) used in generating the plot: Additonal code used was developed NIST! Standards in the food and beverages industry is also the main product from the ( Engl ( 14 PP 118. Cell assays of chemical compounds, Advances in Chemistry Series no solvents chemical... Vacuolization of zona fasciculata in the synthesis of agrochemicals, as a lubricant and materials moist surfaces! Amount present, form soluble metal complexes which are not removed by subsequent control... Have widespread use 1 2 4 trichlorobenzene structure consumer products that are readily available to the legacy brand, ( )... Conducted prior to 1990 ; newer information has not been evaluated 1 2 4 trichlorobenzene structure exclusive from! Happens to trichlorobenzenes ( rivers and lakes ) the main product from atmosphere! Soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be difficult to dose in cell medium! Its best efforts to deliver a high quality copy of the Standard enthalpies of formation of.. Ask a question, provide feedback, or report a problem this may be an fate. Are readily available to the accuracy of a non-federal website is governed by Transl data,,... Not be liable for any damage that may result from data Program, but an...

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